Psoriasis is a common, benign skin disorder. The course of the disease is almost always chronic. The typical features of psoriasis are sharply defined; red, raised, with silver-white scales covered skin areas that itch partially. Psoriasis is not yet curable – but there are some ways to permanently relieve the symptoms! However, the use of CBD in psoriasis and other skin diseases shows promising results. In the following lines, we will explain how CBD can help with skin diseases like psoriasis.
What is Psoriasis?
Psoriasis is an inflammatory skin disease. It is caused by an autoimmune reaction: The immune system is directed against cells of the epidermis, the keranocytes. This false reaction causes these cells to multiply excessively. The result? The skin thickens and gets scaly. The causes are not completely clear yet.
The 3 Ways CBD can help with Psoriasis
As already known in the scientific and medical world, cannabinoids are not restricted only to a specific mode of action. Because through the actual effect, via the body’s own cannabinoid system, the so-called endocannabinoid system, many body processes are regulated, stimulated and also suppressed. But specific properties are also attributed to this cannabinoid.
- CBD is a strong anti-inflammatory substance, and this attributeis largely due its immunosuppressive properties.
- Furthermore, CBD should have antipruritic properties, which can alleviate skin irritation.
Together, these 3 properties of CBD are thought to represent a potentially effective remedy for psoriasis and other skin diseases. Let’s take a closer look at these properties.
Antipruritic Properties of CBD
To alleviate skin irritation, so-called antipruritic drugs are used to relieve the itching of many psoriasis patients. The word pruritus comes from Latin and means itching.
When investigating cannabinoids and their mode of action in topical application, the antipruritic properties of cannabinoids were found. Thus, according to this study, there should be up to 80% reduction in itching when using cannabinoids in pruritus.
In summary, this study presented the potentially effective and highly tolerated use of cannabinoids in itching of various origins. In addition, with a higher concentration of cannabinoids, it should be even more effective in broader indications. “The more cannabinoids, such as CBD, used as a cream or ointment, the more effective it is to help relieve psoriatic itching.
As is often the case, there are not enough studies in the field of cannabinoids for a particular use. Further research will follow, but the first discoveries already speak for themselves.
The Immunosuppressive Properties of CBD
Psoriasis is considered an autoimmune disease. An autoimmune disease is a disorder of the immune system that, depending on the symptom, either overreacts or its immune reactions are directed against the body’s own structures.
The immune system has no tolerance to harmless antigens and considers them as pathogens. Inflammation is a normal and important process of the body’s immune system to protect the body from infections.
In contrast, chronic inflammation and reactive tissue regeneration are among the autoimmune diseases and can lead to damage to the affected organ.
It is also interesting to know that it was only accidentally discovered that psoriasis is an autoimmune disease when a psoriasis patient received an immunosuppressive drug and the symptoms improved.
In conclusion, the immunosuppressive properties of a substance or drug can be helpful in treating psoriasis. According to researchers, CBD has strong anti-inflammatory properties that are due to the immunosuppressive properties of this substance. This in turn makes CBD a very interesting alternative in the treatment of psoriasis.
CBD & the Endocannabinoid System in Psoriasis
A large proportion of the receptors (interfaces) of the endocannabinoid system are located on the skin.
The endocannabinoid system is the body’s own cannabinoid system that allows cannabinoids to dock and interact with the body.
Two main cannabinoid receptors are described, namely CB1 and CB2 receptors.
And a large part of the CB2 receptors are on the skin.
Our immune system is intertwined with the endocannabinoid system and the supply of phytogenic cannabinoids such as CBD can counteract prevailing cannabinoid deficiency.
Some researchers speak of an endocannabinoid system (ECS) deficiency in which an imbalance of body function can develop, which can also lead to autoimmune diseases.
Other researchers also recognize that the endocannabinoid system “regulates the proper and balanced proliferation, differentiation and survival as well as the immune competence and tolerance of skin cells.
Therefore, some researchers strongly believe that psoriasis patients can achieve a significant relief of the symptoms through treatment with cannabinoids. Not only for psoriasis but for almost all other skin diseases.
- What is the Endocannabinoid System? Human Cannabinoid System
- CBD Effects & the Importance of Homeostasis for the Human Body
CBD can Heal and Protect the Skin
As already mentioned, the skin contains the highest amount of CB2 receptors in the body. CBD is a very powerful antioxidant (even stronger than Vitamin C), which can be used as a lotion, oil or ointment to counteract and also repair free radical damage from sources such as UV rays and environmental pollutants when applied topically.
According to researchers, these cannabinoid receptors in the skin also play a role in regulating oil production in the sebaceous glands. Cannabinoid-based topical products are being developed to treat related problems from acne to psoriasis and to promote faster regeneration of the damaged tissue.
This is also shown by historical documents that cannabis preparations have been used for thousands of years in all cultures of the world for wound healing and skin problems.
Today, an increasing number of people are reporting that they have successfully used concentrated cannabis oil for skin cancer and there are also documented cases where people were able to treat melanomas and carcinomas with CBD and THC products. A topical application has no psychoactive effect, even if THC is in the product.