Depression

This is our library on scientific research related to CBD, the Endocannabinoid System, other cannabinoids and Depression. Below you will find a list of conditions for which there are one or more scientific studies of CBD. The source of these scientific studies relates primarily to PubMed, an online service of the U.S. National Library of Medicine.

Important: The studies that are listed by PubMed are for the most part preclinical research. These relate in most cases to animal experiments with isolated CBD (pure CBD) and not fully extracted CBD extract. Although mammals have cell receptors that respond to cannabinoid compounds, the data collected from animal studies are not always 1: 1 applicable to humans. Always check with your physician before starting a new dietary supplement program. Learn more at: The Basics of CBD Oils and Cannabis as a Therapeutic Agent

Antidepressant-Like and Anxiolytic-Like Effects of CBD
Antidepressant-like effect of delta 9-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa
Antidepressant-like effects of cannabidiol in mice: Possible involvement of 5-HT1A receptors
Antidepressants and Changes in Concentration of Endocannabinoids and N-Acylethanolamines in Rat Brain Structures
Cannabidiol induces rapid-acting antidepressant-like effects and enhances cortical 5-HT/glutamate neurotransmission: role of 5-HT1A receptors
Circulating endocannabinoids and N-acyl ethanolamines are differentially regulated in major depression and following exposure to social stress
Endocannabinoid signaling in the etiology and treatment of major depressive illness
Endocannabinoid system dysfunction in mood and related disorders
Prohedonic Effect of CBD in a Rat Model of Depression
Putative role of endocannabinoid signaling in the etiology of depression and actions of antidepressants
Serum contents of endocannabinoids are correlated with blood pressure in depressed women
The endocannabinoid system and the treatment of mood and anxiety disorders
The therapeutic potential of the endocannabinoid system for the development of a novel class of antidepressants

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