Epilepsy & Seizures

This is our library on scientific research related to CBD, the Endocannabinoid System, other cannabinoids and Epilepsy & Seizures. Below you will find a list of conditions for which there are one or more scientific studies of CBD. The source of these scientific studies relates primarily to PubMed, an online service of the U.S. National Library of Medicine.

Important: The studies that are listed by PubMed are for the most part preclinical research. These relate in most cases to animal experiments with isolated CBD (pure CBD) and not fully extracted CBD extract. Although mammals have cell receptors that respond to cannabinoid compounds, the data collected from animal studies are not always 1: 1 applicable to humans. Always check with your physician before starting a new dietary supplement program. Learn more at: The Basics of CBD Oils and Cannabis as a Therapeutic Agent

Cannabidiol displays antiepileptiform and antiseizure properties in vitro and in vivo
Cannabidiol: promise and pitfalls  
Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders 
Cannabidiol–antiepileptic drug comparisons and interactions in experimentally induced seizures in rats
Cannabidivarin (CBDV) suppressespentylenetetrazole (PTZ)-inducedincreases in epilepsy-related gene expression
Cannabinoids for epilepsy
Cannabis, CBD, and epilepsy – From receptors to clinical response 
CBD exerts anti-convulsant effects in animal models of temporal lobe and partial seizures
CBD Post-Treatment Alleviates Rat Epileptic-Related Behaviors
CBD Treatment for Refractory Seizures in Sturge-Weber Syndrome
Chronic administration of CBD to healthy volunteers and epileptic patients 
Could Cannabidiol be a Treatment Option for Intractable Childhood and Adolescent Epilepsy?
Endocannabinoid system protects against cryptogenic seizures
From the Editors: Cannabidiol and medical marijuana for the treatment of epilepsy
Hypnotic and antiepileptic effects of CBD
Medicinal marijuana stops seizures, brings hope to a little girl
Pharmacology of cannabinoids in the treatment of epilepsy
Protective Effects of Cannabidiol against Seizures and Neuronal Death in a Rat Model of Mesial Temporal Lobe Epilepsy
Report from a Survey of Parents Regarding the Use of Cannabidiol in Mexican Children with Refractory Epilepsy.
Report of a parent survey of cannabidiol-enriched cannabis use in pediatrictreatment-resistant epilepsy
Report of a parent survey of CBD-enriched cannabis use in pediatric treatment-resistant epilepsy 
Seizing an opportunity for the endocannabinoid system
The cannabinoids as potential antiepileptics 
The non-psychotropic plant cannabinoids, cannabidivarin (CBDV) and cannabidiol (CBD), activate and desensitize transient receptor potential vanilloid 1 (TRPV1) channels in vitro: potential for the treatment of neuronal hyperexcitability
Therapeutic effects of cannabinoids in animal models of seizures, epilepsy, epileptogenesis, and epilepsy-related neuroprotection

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