PTSD

This is our library on scientific research related to CBD, the Endocannabinoid System, other cannabinoids and PTSD. Below you will find a list of conditions for which there are one or more scientific studies of CBD. The source of these scientific studies relates primarily to PubMed, an online service of the U.S. National Library of Medicine.

Important: The studies that are listed by PubMed are for the most part preclinical research. These relate in most cases to animal experiments with isolated CBD (pure CBD) and not fully extracted CBD extract. Although mammals have cell receptors that respond to cannabinoid compounds, the data collected from animal studies are not always 1: 1 applicable to humans. Always check with your physician before starting a new dietary supplement program. Learn more at: The Basics of CBD Oils and Cannabis as a Therapeutic Agent

A current overview of cannabinoids and glucocorticoids in facilitating extinction of aversive memories: potential extinction enhancers
Bidirectional Effects of CBD on Contextual Fear Memory Extinction
Cannabinoid modulation of fear extinction brain circuits: A novel target to advance anxiety treatment
Cannabinoids and traumatic stress modulation of contextual fear extinction and GR expression in the amygdala-hippocampal-prefrontal circuit
CBD blocks long-lasting behavioral consequences of predator threat stress: Possible involvement of 5HT1A receptors
CBD disrupts the consolidation of specific and generalized fear memories via dorsal hippocampus CB1 and CB2 receptors
CBD Modulates Fear Memory Formation Through Interactions with Serotonergic Transmission in the Mesolimbic System
Effectiveness of Cannabidiol Oil for Pediatric Anxiety and Insomnia as Part of Posttraumatic Stress Disorder: A Case Report
Enhancing cannabinoid neurotransmission augments the extinction of conditioned fear
Mitigation of post-traumatic stress symptoms by Cannabis resin: A review of the clinical and neurobiological evidence
Modulation of Fear Memory by Dietary Polyunsaturated Fatty Acids via Cannabinoid Receptors
Non-antidepressant long-term treatment in post-traumatic stress disorder
Reductions in circulating endocannabinoid levels in individuals with post-traumatic stress disorder following exposure to the world trade center attacks
Stress switches cannabinoid type-1 (CB1) receptor-dependent plasticity from LTD to LTP in the bed nucleus of the stria terminalis
The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: Involvement of the endocannabinoid system
The endocannabinoid system and extinction learning
The endocannabinoid system provides an avenue for evidence-based treatment development for PTSD
The Use of Medicinal Marijuana for Posttraumatic Stress Disorder: A Review

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