Sleep Disorders

This is our library on scientific research related to CBD, the Endocannabinoid System, other cannabinoids and Sleep Disorders. Below you will find a list of conditions for which there are one or more scientific studies of CBD. The source of these scientific studies relates primarily to PubMed, an online service of the U.S. National Library of Medicine.

Important: The studies that are listed by PubMed are for the most part preclinical research. These relate in most cases to animal experiments with isolated CBD (pure CBD) and not fully extracted CBD extract. Although mammals have cell receptors that respond to cannabinoid compounds, the data collected from animal studies are not always 1: 1 applicable to humans. Always check with your physician before starting a new dietary supplement program. Learn more at: The Basics of CBD Oils and Cannabis as a Therapeutic Agent

Cannabis, Cannabinoids, and Sleep: a Review of the Literature
Cannabis, pain, and sleep: Lessons from therapeutic clinical trials of Sativex 
CBD modulates sleep in rats 
Effect of Delta-9-tetrahydrocannabinol and cannabidiol on nocturnal sleep and early-morning behavior in young adults
Effectiveness of Cannabidiol Oil for Pediatric Anxiety and Insomnia as Part of Posttraumatic Stress Disorder: A Case Report.
Effects of acute systemic administration of CBD on sleep-wake cycle in rats
Endocannabinoid modulation of cortical up-states and NREM sleep
Endocannabinoid Signaling Regulates Sleep Stability
Intranodose ganglion injections of dronabinol attenuate serotonin-induced apnea in Sprague-Dawley rat
The nonpsychoactive Cannabis constituent cannabidiol is a wake-inducing agent

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