Stress

This is our library on scientific research related to CBD, the Endocannabinoid System, other cannabinoids and Stress. Below you will find a list of conditions for which there are one or more scientific studies of CBD. The source of these scientific studies relates primarily to PubMed, an online service of the U.S. National Library of Medicine.

Important: The studies that are listed by PubMed are for the most part preclinical research. These relate in most cases to animal experiments with isolated CBD (pure CBD) and not fully extracted CBD extract. Although mammals have cell receptors that respond to cannabinoid compounds, the data collected from animal studies are not always 1: 1 applicable to humans. Always check with your physician before starting a new dietary supplement program. Learn more at: The Basics of CBD Oils and Cannabis as a Therapeutic Agent

Cannabinoid receptor activation prevents the effects of chronic mild stress on emotional learning and LTP in a rat model of depression
Cannabinoids ameliorate impairments induced by chronic stress to synaptic plasticity and short-term memory
Chronic Stress Impairs α1-Adrenoceptor-Induced Endocannabinoid-Dependent Synaptic Plasticity in the Dorsal Raphe Nucleus
Downregulation of endocannabinoid signaling in the hippocampus following chronic unpredictable stress 
Endocannabinoid-mediated modulation of stress responses: Physiological and pathophysiological significance
Endocannabinoids and stress
Endogenous cannabinoid signaling is essential for stress adaptation 
Functional interactions between stress and the endocannabinoid system: from synaptic signaling to behavioral output
Low-frequency stimulation evokes serotonin release in the nucleus accumbens and induces long-term depression via production of endocannabinoid
Neuromodulators, stress and plasticity: a role for endocannabinoid signalling
Regulation of endocannabinoid signaling by stress: Implications for stress-related affective disorders
Stress regulates endocannabinoid-CB1 receptor signaling
The anxiolytic effect of CBD on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system

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